The Database for Annotation, Visualization and Integrated Discovery (DAVID)
provides a comprehensive set of functional annotation tools for investigators to understand the biological meaning behind large lists of genes. These tools are powered by the comprehensive DAVID Knowledgebase built upon the DAVID Gene concept which pulls together multiple sources of functional annotations. For any given gene list, DAVID tools are able to:
Identify enriched biological themes, particularly GO terms
Discover enriched functional-related gene groups
Cluster redundant annotation terms
Visualize genes on BioCarta & KEGG pathway maps
Display related many-genes-to-many-terms on 2-D view.
Search for other functionally related genes not in the list
List interacting proteins
Explore gene names in batch
Link gene-disease associations
Highlight protein functional domains and motifs
Redirect to related literatures
Convert gene identifiers from one type to another.
- Multiple positions available in LHRI
The Laboratory of Human Retrovirology and Immunoinformatics (LHRI) has collaborated with the National Institute of Allergy and Infectious Diseases (NIAID) and supported NIAID clinical trials for patients infected with HIV mutants resisting anti-retroviral therapy. LHRI has isolated the multiple-class drug-resistant (MDR) variants from patients and characterized each variant's drug sensitivity and infectivity. The study aims to define salvage therapy and develop novel therapy (chemotherapy and immunotherapy). During the investigation, LHRI has characterized the emergence of novel mutations on drug susceptibility and viral replication. LHRI is a pioneer in researching the anti-viral cytokine, Interleukin-27, DNA-repair protein (Ku70)-mediated innate immune response against HIV and other virus co-infection, and novel subsets of immune cells. LHRI maintains the Database for Annotation, Visualization and Integrated Discovery ( DAVID ).
(2) Scientist-Cytokines and HIV available in our Basic Research Section. We are looking for a cytokine immunologist who is interested in virus (HIV/ HSV/KHSV) pathogenesis in myeloid immune cell types ( macrophages, dendritic cells and microglia cells).
(3) Postdoctoral Fellow available in our Basic Research Section. This position is an excellent opportunity for a young Ph.D. who has no experience in virus research and seeks a career in a new research field. You will learn how to handle infectious RNA viruses and investigate the mechanism of virus infection and the interaction of host cell proteins using HIV (lentivirus) variants under an SOP following the NIAID guideline in the BSL2* laboratory. LHRI does not consider virus experience in the past, instead seeks a highly motivated researcher. The knowledge learned in the lab can apply to future COIVD or other virus studies.
- DAVID Forum
Forum for DAVID users to ask questions, suggest new functions and help other users by answering their questions.
Frequently Asked Questions
- LHRI Publications
Publications of the Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research
- DAVID Publications
Publications about DAVID
June 15, 2022
DAVID Knowledgebase v2022q2 released.
June 2, 2022
DAVID 6.8 has been retired.
April 26, 2022
DAVID Knowledgebase v2022q1 released.
March 26, 2022
The latest DAVID publication in Nucleic Acids Research is now available in PubMed.
February 19, 2022
DAVID 2021 Update released on our production site with DAVID Knowledgebase v2021q4. DAVID 6.8 can still be found on our development site.
DAVID 2021 Update released on our development site with DAVID Knowledgebase v2021q4.
November 13, 2020
Updated the DAVID header menu and home page.
October 31, 2020
DAVID v6.7 has been retired.
October 28, 2020
NEW Feature: Species selection feature added to List Upload and Conversion Tool when using Official Gene Symbol.
September 1, 2020
False discovery rate (FDR) has been changed from approximate FDR to adaptive FDR. Documentation for Benjamini and FDR has been updated.
July 24, 2020
The DAVID forum has been moved to https://david-bioinformatics.freeforums.net
- > 57K Citations (Updated 2/2/2022)
- Average Daily Usage: ~2,700 gene lists/sublists from ~900 unique researchers.
- Average Annual Usage: ~1,000,000 gene lists/sublists from >100 countries