LHRI Presentations
LHRI Presentations
| 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
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Last updated February 2021 |
2021 Presentations
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S. Goswami, X. Hu, J. Yang, S. Laverdure, J. Qiu, Q. Chen, B.T. Sherman, W. Chang, and T. Imamichi. Identification of A Novel Anti-HIV miRNA in Interleukin-27-differentiated Macrophages. CROI; 1. 2021.Abst. 02161. (Oral presentation in Science Spotlight), Young investigator award.
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2020 Presentations
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B. T. Sherman, M. Hao, J. Qiu, X. Jiao, T. Imamichi, W. Chang. DAVID update-Expanded knowledgebase and analysis tools for the functional annotation of gene lists. CSHL Biological Data Science Conference; 2020 November 4 - November 6, Virtual Meeting, Poster 57.
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H. Sui, Q. Chen, J. Yang, S. Srirattanapirom, and T. Imamichi. Manganese Enhances Ku70-STING mediated IFN-lambda 1 Induction by Increasing in phosphorylation of TBK1. Cytokine 2020; November 1-4, CYT20-1187.
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S. Goswami, X. Hu, Q. Chen, J. Qiu, J. Yang, D. Poudyal, BT. Sherman, W. Chang, and T. Imamichi, A Comparative Study of Novel microRNAs Identified in Interleukin-27-Induced HIV-Resistant T Cells. Cytokine 2020; November 1-4, CYT20-1150.
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H Imamichi, V Natarajan, F Scrimieri, M Smith, Y Badralmaa, M Bosche, J Hensien, T Buerkert, W Chang, B Sherman, K Singh, HC Lane. Multiple sanctuary sites for intact and "defective" HIV-1 in post-mortem tissues in individuals with suppressed HIV-1 replication: Implications for HIV-1 cure strategies. 23rd International AIDS Conference; 2020 July 6 - July 10, Virtual Meeting, Oral presentation OAA0404.
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B. Sherman, X. Hu, K. Singh, L. Haine, J. Neaton, JD. Lundgren, T. Imamichi, W. Chang, H. Clifford Lane, for the INSIGHT Study Group. Genetic Determinants of hsCRP, D-dimer, and IL-6 in 3 Multiethnic HIV Cohorts. The 2020 Conference on Retroviruses and Opportunistic Infections; (Boston, Massachussetts), 2020 March 8 - March 11; Poster 195.
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2019 Presentations
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| H. Sui, HC. Lane and T. Imamichi. Ku70, a Nuclear Protein Associated with Non-homologous End-joining (NHEJ) Pathway of DNA Repair, Translocates to the Cytosol upon Exogenous DNA Stimulation to Induce Type III Interferon Response. Poster presented at the Spring Research Festival at NCI-Frederick; 2019 May 1-2; Fort Detrick, Frederick, MD.
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| X. Hu, B. Sherman, J. Qiu, S. Laverdure, T. Imamichi. CLAP: a comprehensive lncRNA analysis pipeline. Poster presented at the Spring Research Festival at NCI-Frederick; 2019 May 1-2; Fort Detrick, Frederick, MD.
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H. Sui, J. Yang, X. Hu, Q. Chen, and T. Imamichi. Identification of a unique RNA motif sequence that regulates an off-target effect by small RNA. Keystone Symposia: Small Regulatory RNAs; (Daejeon Korea), April 14 - April 18, 2019. Abs 1032.
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H. Sui, HC. Lane and T. Imamichi. Ku70, A Nuclear Protein Associated with Non-homologous End-joining (NHEJ) Pathway of DNA Repair, Translocates to the Cytosol upon Exogenous DNA Stimulation to Induce Type III Interferon Response. Innate Immune Receptors: Roles in Immunology and Beyond; (Taipei, Taiwan), Mar 10 - Mar 14, 2019. Abst.
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2018 Presentations
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H. Sui, J.Yang, X. Hu, Q. Chen, H.C. Lane and T. Imamichi. siRNAs Containing a Unique 5-nucletide Motif Act as a Quencher of IFI16-mediated DNA Sensing in Innate Immune Response. Cytokine 2018; (Boston, MA), October 27-30, 2018. Abst. P247.
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S. Laverdure, Z. Wang, K. Nagashima, H.C. Lane and T. Imamichi. IL-27 triggers autophagy in macrophages via a mTOR and LC3-Independent Manner. Cytokine 2018; (Boston, MA), October 27-30, 2018. Abst. P043.
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S. Laverdure, Z. Wang, K. Nagashima, H.C. Lane and T. Imamichi. IL-27 induces autophagy during monocyte-to-macrophage differentiation through a novel LC3-independent pathway. Oral and Poster presentation. Immunology 2018; (Austin, TX), May 4-8. Abst. 164.7.
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H. Sui, H.C. Lane and T. Imamichi. Human Ku70, a nuclear protein associated with non-homologous end-joining (NHEJ) pathway of DNA repair, is translocated to the cytosol upon exogenous DNA stimulation and serves as a DNA sensor to induce IFN-lambda 1 (Type-III IFN) via a STING dependent manner. Keystone Symposia. Cells vs. Pathogen: Intrinsic Defenses and Counter defenses; (Monterey, California), USA, March 23-26, 2018. Abs. 1048.
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D. Poudyal, A. Herman, J. Adelsberger, J. Yang, X. Hu, Q. Chen, M. Bosche, B. T. Sherman, and T. Imamichi. A novel IL-27-stimulated microRNA, hsa-miR-6852 (miR SX4) induces necrosis in cervical cancer cells by downregulating the FoxM1 expression by unconventional microRNA pathway. Keystone Symposia. Noncoding RNAs: Form, Function, Physiology;(Keystone, Colorado), USA, Feb 25 - Mar 1, 2018.
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2017 Presentations
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Y. Saito, B. Sowrirajan, D. Poudyal, N. Noguchi, HL. Malech, H.C. Lane and T. Imamichi. Interleukin-27 Induces p47phox in Monocyte-derived Macrophages and Dendritic cells and Enhances the Potential of Reactive Oxygen Species Generation. Abstract presented at the Society for Redox Biology and Medicine 2017; 2017 November 29 - December 2; Baltimore, MD. Abs 321.
[https://doi.org/10.1016/j.freeradbiomed.2017.10.334]
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T. Izumi, D. Poudyal, J. Yang, X. Hu, M. Bosche, Q. Chen, W. Bruchey, R.G. Zamat, B.T. Sherman, H.C. Lane, and T. Imamichi. IL-27-inducible novel microRNA, hsa-mir-7705, predominantly elicits IFN-alpha from human monocyte-derived macrophages in a structure and sequence dependent manner. Poster presented at the 5th Annual Meeting of the International Cytokine & Interferon Society; 2017 October 29 - November 2; Kanazawa, Japan. Poster Abs. Mo-P11-12.
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H. Sui, X. Hu, B.T. Sherman, H.C. Lane, and T. Imamichi. siRNA with a Unique 5-Nt Motif Potently Suppresses IFI16-Mediated Innate Immune Response to Intracellular DNA. Poster presented at the 5th Annual Meeting of the International Cytokine & Interferon Society; 2017 October 29 - November 2; Kanazawa, Japan. Poster Abs. Tu-P4-14.
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| X. Hu, Q. Chen, B. Sowrirajan, M. Bosche, T. Imamichi and B. T Sherman. MicroRNA Expression Profiling and Novel MicroRNA discovery in Interleukin-27 Treated Monocyte-derived Human Dendritic Cell. Poster presented at the 7th Genomics & Big Data Summit; 2017 September 26-27; San Diego, CA.
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| X. Jiao, H. Imamichi, T. Rehman, R. Nahar, R.L. Dewar H. C. Lane, T. Imamichi and B.T. Sherman. Self-Tuning Spectral Clustering for Full-length Viral Quasispecies Reconstruction with PacBio Long Reads. Poster presentation at the Proceedings of ACM-BCB; 2017 August 20-23; Boston, MA.
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| B. Sowrirajan, J. Yang, J. Adelsberger, M. Bosche, Q. Chen, C. Watkins, T.Izumi, H. Clifford Lane, and T. Imamichi. Interleukin-27 (IL-27) differentiates monocytes into HIV resistant dendritic cells: Identification of ANKRD22 as a novel inducible host restriction factor. Oral presentation at the 42nd annual meeting on Retroviruses; 2017 May 22-26; Cold Spring Harbor, NY.
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| T. Izumi, D. Poudyal, Q. Chen, X. Hu, BT. Sherman, and T. Imamichi. The Antiviral Mechanism of a Novel MicroRNA, miR 7705 in Macrophage induced by IL-27 Treatment. Poster presented at the Spring Research Festival at NCI-Frederick; 2017 May 2-3; Fort Detrick, Frederick, MD.
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| T. Rehman, A. Khan, H. Highbarger, P. Burbelo, B. Sherman, X. Hu, T. Imamichi, J. Metcalf , J. Beigel, C. Lane, M. Baseler, and RL. Dewar. A New Method to Test for Zika Virus? Poster presented at the Spring Research Festival at NCI-Frederick; 2017 May 2-3; Fort Detrick, Frederick, MD.
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| H. Sui, M. Zhou, H. Imamichi, H. C. Lane and T. Imamichi. Identification of STING as an essential adaptor of Ku70 to initiate cytosolic DNA or DNA virus-mediated IFN-Λ1 innate immune response. Poster presented at the Spring Research Festival at NCI-Frederick; 2017 May 2-3; Fort Detrick, Frederick, MD.
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| X. Hu, Q. Chen, B. Sowrirajan, M. Bosche, T. Imamichi and BT. Sherman. Identification of Novel miRNAs and miRNA Expression Profiling in Interleukin-27 Treated Monocyte-derived Human Dendritic Cells. Poster presented at the Spring Research Festival at NCI-Frederick; 2017 May 2-3; Fort Detrick, Frederick, MD.
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| D. Poudyal, Q. Chen, J.W. Adelsberger, J. Yang, RL. Homung, HC. Lane, T. Imamichi. A DNA- and RNA- binding protein, Y-Box Binding Protein-1 (YB-1) is a novel host required factor in CD4 T cells regulated by post-translational modification by Interleukin-27 (IL-27). Poster presented at the Keystone Symposia, Modeling Viral Infections and Immunity; 2017 May 1-4; Estes Park, Colorado.
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| H. Sui, M. Zhou, H. Imamichi, H. C. Lane and T. Imamichi. Identification of STING as an essential adaptor of Ku70-medited IFN-Λ1 induction in sensing intracellular DNA. Poster presented at the Keystone Symposia, Pattern Recognition Signaling: From Innate Immunity to Inflammatory Disease (X5); 2017 March 19-23; Banff, Alberta Canada.
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2016 Presentations
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| H. Sui, M. Zhou, X. Jiao, H. Imamichi, B.T. Sherman, H.C. Lane, and T. Imamichi. STING Is an Indispensable Adaptor in DNA Via Ku70-Mediated IFN-Λ1 Signalling Pathway. Poster presented at the Nucleic Acid Sensing Pathways: Innate Immunity, Immunobiology and Therapeutics (E2); 2016 May 8-12; Dresden, Germany.
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| B.T. Sherman, J.H. Beigel, X. Hu, J. Qiu, M. Bosche, J. Yang, R.A. Lempicki, H.C. Lane, R.T. Davey Jr., and T. Imamichi. Gene Expression Profiles Associated with a Recombinant Vesicular Stomatitis Virus Ebola Vaccine. Poster presented at the Spring Research Festival; 2016 May 3-4; Fort Detrick, Frederick, MD.
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| J. Qiu, S. Swaminathan, A.W. Rupert, Z. Hu, J. Higgins, R.L. Dewar, R. Stevens, Q. Chen, C.A. Rehm, J.A. Metcalf, M.W. Baseler, B.T. Sherman, H.C. Lane, and T. Imamichi. Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation. Poster presented at the Spring Research Festival; 2016 May 3-4; Fort Detrick, Frederick, MD.
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| X. Jiao, T. Rehman, Q. Chen, H. Imamichi, R.L. Dewar, H.C. Lane, T. Imamichi, and B.T. Sherman. A Workflow for Viral Quasi-Species Analysis with Pacbio Long Reads. Poster presented at the Spring Research Festival; 2016 May 3-4; Fort Detrick, Frederick, MD.
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| X. Hu, Q. Chen, B. Sowrirajan, H.C. Lane, T. Imamichi, and B.T. Sherman. Genome-Wide Identification of Novel Micrornas in Human Monocyte-Derived Dendritic Cells. Poster presented at the Spring Research Festival; 2016 May 3-4; Fort Detrick, Frederick, MD.
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