Dr. Dawei Huang's Talk Was Highlighted by GenomeWeb -2014

Dr. Dawei Huang's Talk Was Highlighted by GenomeWeb -2014

Postby david » Thu Mar 19, 2015 3:19 pm

Dr. Dawei Huang's presentation at the ABRF (Albuquerque, 2014) was highlighted by the GenomeWeb.

"Long-read sequencing can enable researchers to not only detect what drug-resistance mutations are present in someone with HIV, but also whether those mutations are present in one strain or spread across multiple strains of the virus circulating in that patient, according to a presentation at the Association of Biomolecular Resource Facilities annual conference, held here this week.

Dawei Huang, a supervisor at the DAVID Bioinformatics Lab, noted in a talk at the ABRF conference that Sanger sequencing is currently used to detect drug resistance mutations in HIV, but the sensitivity of that approach limits its ability to perceive minor mutations. While he noted that next-generation sequencing improves upon that sensitivity to detect rare mutations, newer long-read approaches can detect both mutations and quasi-species of the HIV virus..........."

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