| DAVID
Gene Accession Conversion Tool |
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1. Introduction
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This tool was built based
on the "DAVID Gene Concept", a graph theory evidence-based method to
agglomerate species-specific gene/protein identifiers the most popular
resources including NCBI, PIR and Uniprot/SwissProt. It groups tens of
millions of identifiers into 1.5 million unique protein/gene records.
With the most comprehensive accession mapping system in DAVID 2.1, any
given gene accession can be quickly mapped to another based on the
user's
choice. The tool also automatically suggests possible choices for the
ambiguous gene accessions in the list.
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2.
Choose Gene List to be
Convertedand and the Targeting
Gene Identifier Type
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3. The Result Page |
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The Right Panel:
It displays the
result for the genes that has been successfully
converted to desired accessions/ids of user?s choice. If a gene has
multiple choices for destination accessions, they all will be displayed
in independent rows.
The Left Panel:
It displays the
statistics summary of gene accession conversion. For
any ambiguous gene accessions, the possible conversion choices will be
suggested by DAVID system and upon user?s decision for further
conversion.
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4. Download/Save Results/Get Back to DAVID with Converted Gene
IDs
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Option 1:
highlight
result content -> copy/paste to favorite text editor or
excel sheet.
Option 2:
right mouse
button click on ?download the list? ->select save target
as-> choose destination folder -> type a favorite file name, like
?myList.txt?.
Option 3:
Click on big button on the top of right panel. It will bring back to
DAVID for other analytical tools. You also find the gene IDs just
converted automatically appear as a new gene list in DAVID Gene List
manager.
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5. Terminology For "Conversion Summary" Table
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"In DAVID DB" Column: In
order to successful convert gene accession from on to the other, the
user input accession has to be a valid one as user claimed in DAVID
Knowledgebase. "Yes"
means that DAVID mapping system covers that accession according to user
claimed ID type; "No"
means it is not a valid one in any types of gene IDs in entire DAVID
knowledgebase, and the reasons could be: typo,
completely retired accessions/ids, etc.; "Ambiguous"
means that user's accession is not good as user claimed. However, it
could be other types of gene identifiers. In this case, the detail
choices will be following in next table space.
"Coversion" Column:
"Successful"
means the corresponding desired accessions/IDs have been found; "None"
means the desired accessions/IDs is not available; "Pending" means
the mapping job not waiting for ambiguous ones unpon user's decision.
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Last Updated: Feb.
2007
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